发布时间:2024/5/2 8:04:34 阅读人数:14
MCE 站:Datopotamab
CAS:2267989-53-5
品牌:MedChemExpress (MCE)
存储条件:Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性:Datopotamab (CDP7657) 是一种靶向 TROP2 的抗体。Datopotamab 可用于合成 Datopotamab deruxtecan (HY-141598),一种 TROP2 定向抗体活性分子偶联物 (ADC)。Datopotamab deruxtecan 由 DNA 拓扑异构酶 I 抑制剂 Deruxtecan (HY-13631E) 和 Datopotamab 组成。
热销产品:Fludarabine (phosphate) | N1,N11-Diethylnorspermine (tetrahydrochloride) | Macitentan | Iohexol-d5 | Temsirolimus | Dehydroepiandrosterone sulfate | Febuxostat | COG 133 (TFA) | HEPES | α-Vitamin E
研究领域:Antibody-drug Conjugate/ADC Related
作用靶点:ADC Antibody
热门产品线:重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物 | 寡核苷酸
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
参考文献:
[1]. Okajima D, et al. Datopotamab Deruxtecan, a Novel TROP2-directed Antibody-drug Conjugate, Demonstrates Potent Antitumor Activity by Efficient Drug Delivery to Tumor Cells. Mol Cancer Ther. 2021 Dec;20(12):2329-2340.
原创作者:MedChemExpress
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