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Pericyazine

CAS No. : 2622-26-6

MCE 站：Pericyazine

产品活性：Pericyazine (Propericiazine) 是代抗精神病药物，被用作短期管理严重焦虑状态和精神病的辅助药物。Pericyazine (Propericiazine) 是一种选择性的 D2 多巴胺受体 (D2-dopamine receptor) 拮抗剂。Pericyazine 具有肾上腺溶解、抗胆碱能和锥体外系作用。

研究领域：GPCR/G Protein  |  Neuronal Signaling

作用靶点：Dopamine Receptor

In Vivo: Studies in rodents show that Pericyazine is able to produce potentiation of ether and hexobarbital narcosis and morphine analgesia. It also has hypothermic activity and produces depression of spontaneous motor activity in mice. On a milligram potency basis, Pericyazine is more potent than chlorpromizine in the potentiation of barbiturate narcosis test and the blocking of conditioned avoidance in rats. Pericyazine demonstrates analgesic properties similar to methotrimeprazine in mice and rats and produces adrenergic blocking effects in mice and dogs.

相关产品：FDA-Approved Drug Library Plus  |  Drug Repurposing Compound Library  |  FDA-Approved Drug Library Mini  |  Orally Active Compound Library  |  GPCR/G Protein Compound Library  |  Neuronal Signaling Compound Library  |  Neurotransmitter Receptor Compound Library  |  Anti-COVID-19 Compound Library  |  FDA-Approved Drug Library  |  Drug Repurposing Compound Library Plus  |  Bioactive Compound Library Plus  |  FDA Approved & Pharmacopeial Drug Library  |  MPTP hydrochloride  |  Clozapine N-oxide  |  Chlorpromazine hydrochloride  |  Oxidopamine hydrobromide  |  Deschloroclozapine  |  SCH-23390 hydrochloride  |  Bromocriptine mesylate  |  Pimozide  |  Trifluoperazine dihydrochloride  |  Risperidone  |  L-DOPA  |  SKF 38393 hydrochloride  |  Thioridazine hydrochloride  |  Fluphenazine dihydrochloride  |  Cabergoline  |  Olanzapine  |  Sertindole  |  Haloperidol  |  Brexpiprazole  |  Domperidone  |  Fenoldopam mesylate  |  Lumateperone tosylate  |  Pergolide mesylate  |  Ropinirole hydrochloride  |  Cariprazine hydrochloride  |  Clomipramine hydrochloride  |  Quetiapine  |  SKF-82958 hydrobromide  |  Triflupromazine hydrochloride

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