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Octreotide acetate

CAS No. : 79517-01-4

MCE 站：Octreotide acetate

产品活性：Octreotide acetate是长效的天然生长抑素合成类似物，是比生长抑素更有效的生长激素，胰高血糖素和胰岛素的抑制剂。

研究领域：GPCR/G Protein  |  Neuronal Signaling

作用靶点：Somatostatin Receptor

In Vivo: Octreotide-treated groups show a significant reduction in the tumor volume when compared with saline group. Octreotide-PPSG (1.4 mg/kg, i.p.) shows greater antitumor effect than Octreotide-soln (100 μg/kg, i.p.). Octreotide-treatments results in significant inhibitory effect on the expression levels of SSTR2 and SSTR5 in primary HCC-bearing rats compared with the saline group. Octreotide-PPSG appears to inhibit the expression of SSTR2 and SSTR5 to a greater extent than that of Octreotide-soln treated group. A test dose of octreotide acetate significantly decreases the serum gastrin level to approximately one third of the baseline in 2 hr and the effect lasted approximately for 6 hr. On day 21, treatment with sustained-release formulation of octreotide acetatea (5 mg intramuscular, q 4 wk) is initiated.

相关产品：Endocrinology Compound Library  |  FDA-Approved Drug Library Plus  |  Covalent Screening Library Plus  |  Drug Repurposing Compound Library  |  FDA-Approved Drug Library Mini  |  Orally Active Compound Library  |  Macrocyclic Compound Library  |  GPCR/G Protein Compound Library  |  Neuronal Signaling Compound Library  |  Covalent Screening Library  |  Peptidomimetic Library  |  Anti-Cardiovascular Disease Compound Library  |  FDA-Approved Drug Library  |  Anti-Cancer Compound Library  |  Drug Repurposing Compound Library Plus  |  NMPA-Approved Drug Library  |  Bioactive Compound Library Plus  |  Immunology/Inflammation Compound Library  |  FDA Approved & Pharmacopeial Drug Library  |  MK-4256  |  Pasireotide ditrifluoroacetate  |  Octreotide  |  CYN 154806 TFA  |  Cortistatin-14 TFA  |  SSTR5 antagonist 1  |  J-2156  |  L-803087  |  PEN-221  |  SSTR5 antagonist 2

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