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产品价格:电议      采购度:1615      原产地:美洲
发布时间:2021/6/2 11:27:04 所属地区:国外 国外
简要描述:
[Leu5]-Enkephalin 是一种具有吗啡药性的五肽。作为阿片受体 (opioid receptors) 激动剂。
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CAS No. : 58822-25-6
MCE 站:[Leu5]-Enkephalin
产品活性:[Leu5]-Enkephalin 是一种具有吗啡药性的五肽。作为阿片受体 (opioid receptors) 激动剂。
研究领域:GPCR/G Protein | Neuronal Signaling | Metabolic Enzyme/Protease
作用靶点:Opioid Receptor | Endogenous Metabolite
In Vitro: Enkephalins (met- , leu-enkephalin, and enkephalin 8) and dynorphins are two classes of opioid peptides found in the spinal dorsal horn. Mu, delta, and kappa are three major subtypes of opioid receptors. Enkephalins are putative endogenous ligands for delta opioid receptors, and dynorphins are endogenous ligands for the kappa opioid receptors. Three receptor types resembling the vertebrate δ- and κ-type opioid receptors have been characterized pharmacologically in nervous tissues (e.g. Ki=18.9 nM for Leu-enkephalin) and localized by autoradiography at CHH terminals in the SG of C. maenas.Leucine-enkephalin is a pentapeptides with morphine like properties, naturally present in mammalian brain.
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更新时间:2024/1/2 10:11:58
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