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产品价格：电议 采购度：1638 原产地：美洲
发布时间：2021/6/2 12:16:14 所属地区：国外 国外
简要描述：
Z-WEHD-FMK 是一种强效具有细胞通透性可逆的 caspase-1/5 抑制剂。Z-WEHD-FMK 也抑制 cathepsin B 的活性 (IC50=6 μM)。Z-WEHD-FMK 可用于检测细胞凋亡。
标签：z-wehd-fmk
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CAS No. : 210345-00-9
MCE 站：Z-WEHD-FMK
产品活性：Z-WEHD-FMK 是一种强效具有细胞通透性可逆的 caspase-1/5 抑制剂。Z-WEHD-FMK 也抑制 cathepsin B 的活性 (IC50=6 μM)。Z-WEHD-FMK 可用于检测细胞凋亡。
研究领域：Apoptosis | Metabolic Enzyme/Protease
In Vitro: Z-WEHD-FMK (80 μM; 9 hours) elicits a near-complete blockage of C. trachomatis-induced cleavage of golgin-84 ａnd increases GM130 expression in cells.
Z-WEHD-FMK (30 min before being exposed to E. piscicida) effectively inhibits 0909I E. piscicida induced ZF4 cells cytotoxicity ａnd pyroptotic morphology. And in addition, it also inhibits the cytotoxicity induced by cytosolic LPS delivery.
Z-WEHD-FMK (20 μM;18-24 hours following Cr3+,Ni2+, ａnd Co2+) significantly induces a decrease of 76% to 86% in IL-1β release with 200 to 400 ppm Cr3+, it also induces a decrease of 35% to 45% with 48 ppm Ni2+ or higher, Finally, this caspase-1 inhibitor induced a decrease with 6 ppm Co2+, down to a level below the detection threshold, ａnd a decrease of 40% to 48% with 12 to 24 ppm Co2+ in bone marrow-derived macrophages (BMDM).
相关产品：Bioactive Compound Library Plus | Apoptosis Compound Library | Metabolism/Protease Compound Library | Anti-Cancer Compound Library | Pyroptosis Compound Library | Z-VAD(OMe)-FMK | Z-DEVD-FMK | Leupeptin hemisulfate | Aloxistatin | Z-IETD-FMK | PMSF | Tauroursodeoxycholate Sodium | N-Ethylmaleimide | E-64 | Emricasan | CA-074 methyl ester | Ac-DEVD-CHO | CA-074 | Calpeptin | Papain | Guggulsterone | Wedelolactone | LY 3000328 | Dehydrocorydaline chloride | Z-YVAD-FMK | Ginsenoside Rh2 | Terfenadine | SID 26681509 | Phenoxodiol | Ac-FLTD-CMK | Crustecdysone | BOC-D-FMK
更新时间：2024/1/2 10:11:58
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