MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。

Glucagon-like peptide 1 (1-37), human TFA

CAS No. :

MCE 站：Glucagon-like peptide 1 (1-37), human TFA

产品活性：Glucagon-like peptide 1 (1-37), human (TFA) is a highly potent agonist of the GLP-1 receptor.

研究领域：GPCR/G Protein

作用靶点：Glucagon Receptor

In Vitro: Glucagon-like peptide-1 (GLP-1) is produced by the posttranslational processing of proglucagon ａnd acts as a regulator of various homeostatic events. GLP-1(1-37) is more stable than GLP-1(7-37), with 94.7% of the initial amount of peptide left after a 4h exposure to mouse serum. GLP-1(1-37) is confirmed to be a highly potent agonist of the GLP-1 receptor (GLP-1R) by measuring the expression of the luciferase reporter gene expression in transiently transfected human embryonic kidney (HEK293) cells.

In Vivo: GLP-1(1–37) decreases glycemic excursion in a dose-dependent. The administration of GLP-1(1–37) or GLP-1(7–37) markedly decrease blood glucose levels at 15 min ａnd 30 min compared with the control group.

相关产品：Bioactive Compound Library Plus  |  Exendin-4  |  Liraglutide  |  Glucagon (1-29), bovine, human, porcine  |  Avexitide  |  Adomeglivant  |  GLP-1(7-37)  |  GLP-1(7-36), amide acetate  |  BETP  |  GLP-2(1-33)(human)  |  GRA Ex-25  |  Cotadutide acetate  |  NNC-0640  |  Taspoglutide  |  GLP-1 moiety from Dulaglutide  |  Glucagon receptor antagonists-2  |  Exendin-3/4 (59-86)  |  FTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS  |  GLP-1(28-36)amide  |  GLP-1(32-36)amide  |  GLP-1(9-36)amide  |  Glucagon receptor antagonists-1  |  GTFTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS  |  HAEGTFT  |  HAEGTFTSD  |  HAEGTFTSDVS