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GLP-1(32-36)amide

CAS No. : 1417302-71-6

MCE 站：GLP-1(32-36)amide

产品活性：GLP-1(32-36)amide，一种衍生自糖调节激素 GLP-1 的 C 末端的五肽。GLP-1(32-36)amide 可抑制糖尿病小鼠的体重增加并调节全身葡萄糖代谢。

研究领域：GPCR/G Protein

作用靶点：Glucagon Receptor

In Vitro: GLP-1(32-36)amide (0.1-10 μM; 24 h) retains cell viability ａnd decreases apoptosis against Streptozotocin (STZ; 1 μM) in INS‐1 cells.

In Vivo: GLP-1(32-36)amide (1 μmol/kg; i.p. once daily for 21 d) protects islet from damage, inhibits weight gain, ａnd relieves symptoms of polydipsia in diabetic mice.
GLP-1(32-36)amide (1 μmol/kg; a single i.p.) slightly reduces the mean glucose lever at 30 min after the challenge of glucose in normal mice.
GLP-1(32-36)amide (50-70 nmol/kg/d; infusion for 12-16 weeks) prevents the development of diet-induced obesity ａnd hepatic steatosis in high fat-fed mice.

相关产品：Bioactive Compound Library Plus  |  GPCR/G Protein Compound Library  |  Diabetes Related Compound Library  |  Exendin-4  |  Liraglutide  |  Glucagon (1-29), bovine, human, porcine  |  Avexitide  |  Adomeglivant  |  GLP-1(7-37)  |  GLP-1(7-36), amide acetate  |  BETP  |  GLP-2(1-33)(human)  |  GRA Ex-25  |  Cotadutide acetate  |  Glucagon-like peptide 1 (1-37), human TFA  |  NNC-0640  |  Taspoglutide  |  GLP-1 moiety from Dulaglutide  |  Glucagon receptor antagonists-2  |  Exendin-3/4 (59-86)  |  FTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS  |  GLP-1(28-36)amide  |  GLP-1(9-36)amide  |  Glucagon receptor antagonists-1  |  GTFTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS  |  HAEGTFT  |  HAEGTFTSD  |  HAEGTFTSDVS

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