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Endocrinology Compound Library

MCE 站：Endocrinology Compound Library

The endocrine system is a chemical messenger system comprising feedback loops of the hormones released by internal glands of an organism directly into the circulatory system, regulating distant target organs. Hormones are chemicals that serve to communicate between organs and tissues for physiological regulation and behavioral activities. Hormones affect distant cells by binding to specific receptor proteins in the target cell, resulting in a change in cell function. The endocrine system is concerned with the integration of developmental events proliferation, growth, and differentiation, and the psychological or behavioral activities of metabolism, growth and development, tissue function, sleep, digestion, respiration, excretion, mood, stress, lactation, movement, reproduction, and sensory perception caused by hormones. Irregulated hormone release, inappropriate response to signaling or lack of a gland can lead to endocrine disease. MCE offers a unique collection of 694 endocrinology related compounds targeting varieties of hormone receptors such as thyroid hormone receptor, TSH receptor, GNRH receptor, adrenergic receptor, etc. MCE Endocrinology Compound Library is a useful tool for the discovery of endocrinology drugs.

Description & Advantages:

?   A unique collection of 694 bioactive compounds which can be used in the research of endocrine regulation.

?   Targets include thyroid hormone receptor, TSH receptor, GNRH receptor, adrenergic receptor related signaling pathways.

?   A useful tool for the discovery of endocrinology drugs.

?   Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

?   Structurally diverse, medicinally active, and cell permeable.

?   Detailed compound information with structure, IC₅₀, and brief introduction.

?   Validated NMR and HPLC to ensure high purity and quality.

?   All compounds are in stock and continuously updated.

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