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Methyl 3,4-dihydroxybenzoate

CAS No. : 2150-43-8

MCE 站：Methyl 3,4-dihydroxybenzoate

产品活性：Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester) 是绿茶中发现的抗氧化多酚的主要代谢产物。 抗氧化和抗炎作用。

研究领域：NF-κB  |  Apoptosis

作用靶点：Keap1-Nrf2  |  Apoptosis

In Vitro: Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester; Methyl protocatechuate) alleviates the toxic effects of F^- via modulating its bioavailability, intracellular calcium level, mitochondrial membrane integrity and redox signaling in A549 cells.

In Vivo: Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester; Methyl protocatechuate) (25 or 50 mg/kg bw/day) prevents the cellular F^- accumulation and oxidative stress. Methyl 3,4-dihydroxybenzoate prevents the inflammatory and associated fibrosis progression by restoring the expression of RAGE and Nrf2.

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