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Pentacosanoic acid

CAS No. : 506-38-7

MCE 站：Pentacosanoic acid

产品活性：Pentacosanoic acid 是一种 25 碳长链饱和脂肪酸，是戊酸的共轭酸。

研究领域：Metabolic Enzyme/Protease

作用靶点：Endogenous Metabolite

In Vivo: The degree of demyelination in adrenoleukodystrophy is related to the Pentacosanoic to Docosanoic acid ratios (C25:0/C22:0 and C26:0/C22:0). Mainly saturated fatty acids of the middle class components (C24:0, C25:0 and C26:0) are found in severely affected areas where the active process is complete. Because a region of high long chain fatty acid content, lacking histopathological change, is detected.
The area with myelin destruction with axonal preservation is generally most prominent in the frontal edge of the lesion. A bell-shaped distribution of very long chain fatty acids, esterified to cholesterol, are detectable, with the mid-point being formed by Pentacosanoic (C25 : 0) and Hexacosanoic (C26 : 0) acids.

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