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Argireline acetate

CAS No. :

MCE 站：Argireline acetate

产品活性：Argireline acetate (Acetyl hexapeptide-3 acetate) 是一种无毒，可渗透皮肤的抗皱肽。Argireline acetate 可显着抑制神经肌肉接头处依赖 Ca²⁺ 的神经递质释放。Argireline acetate 具有抗皱和抗衰老的作用。

研究领域：Others

作用靶点：Others

In Vitro: The incubation of Argireline solution in different concentrations with human embryonic kidney HEK-293 (IC50 of 34.862 μM) and neuroblastoma IMR-32 cells (IC50 of 68.458 μM)) for 48 h have dose dependent antiproliferative effect. Argireline solution incubated in different concentrations with HSF has a dose-dependent antiproliferative effect on those cells. Cellular proliferation is not effected in Argireline low concentration.

In Vivo: Argireline is applied to the aged mice twice daily for 6 weeks. There is an improvement in the histological structure of skin tissue in the aged mice; the amount of type I collagen fibers increased, while that of type III collagen fibers decreased. Argireline could improve the histological structure of skin tissue and rejuvenate the aging skin.

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