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ATP disodium trihydrate

CAS No. : 51963-61-2

MCE 站：ATP disodium trihydrate

产品活性：ATP disodium trihydrate (Adenosine 5'-triphosphate disodium trihydrate) 是体内能量储存和代谢的重要物质，为代谢提供能量，同时在细胞中作为辅酶发挥作用。ATP disodium trihydrate 是免疫和炎症中重要的内源性信号分子。

研究领域：Metabolic Enzyme/Protease

作用靶点：Endogenous Metabolite

In Vitro: ATP disodium trihydrate (5 mM; 1 hour) co-treatment with LPS (1 μg/mL) has a synergistic effect on the activation of the NLRP3 inflammasome in HGFs.
ATP disodium trihydrate (2 mM; 0.5-24 hours) induces secretion of IL-1β, KC and MIP-2 from BMDMs in a caspase-1 activation-dependent manner.
ATP disodium trihydrate promotes neutrophil chemotaxis in vitro.

In Vivo: ATP disodium trihydrate (50 mg/kg; i.p.) protects mice against bacterial infection in vivo.
ATP disodium trihydrate induces the secretion of IL-1β, KC and MIP-2 and neutrophils recruitment in vivo.

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