MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。

Fibronectin

CAS No. : 86088-83-7

MCE 站：Fibronectin

产品活性：Fibronectin 是存在于血液和细胞中的糖蛋白(~500 kDa)，是组织损伤的生物标记物。Fibronectin 可与整合素结合。Fibronectin 还与其它细胞外基质蛋白如胶原蛋白、纤维蛋白和硫酸肝素蛋白聚糖结合。

研究领域：Cytoskeleton

作用靶点：Integrin

In Vitro: Fibronectin (FN) is a glycoprotein present in blood as well as in cells. While Fibronectin (FN) in blood has many functions, its primary role is to promote wound repair following injury. Increases in plasma Fibronectin (FN) has been reported after inflammation, trauma, and diseases such as atherosclerosis. Tobacco-related lung diseases are characterized by increased accumulation of Fibronectin (FN) which can be induced by nicotine. We found significant increases of plasma Fibronectin (FN) following exposure to e-cig aerosols and TS. Although our study examined the levels of 8-oxodG, CRP, and Fibronectin (FN), additional markers for lung injury need be explored in future studies.
Fibronectin also binds to other extracellular matrix proteins such as collagen, fibrin, and heparan sulfate proteoglycans (e.g. syndecans) .

相关产品：Cilengitide  |  iRGD peptide  |  GLPG0187  |  MK-0429  |  E7820  |  ATN-161 trifluoroacetate salt  |  Cucurbitacin B  |  Leukadherin-1  |  RGD Trifluoroacetate  |  Arg-Gly-Asp-Ser  |  Eptifibatide  |  OSU-T315  |  A-205804  |  Cyclo(-RGDfK) TFA  |  RGD peptide (GRGDNP) (TFA)  |  Cyclo(RGDyK) trifluoroacetate  |  TR-14035  |  GRGDSP TFA  |  Tetrac  |  Tirofiban hydrochloride monohydrate  |  ILK-IN-3  |  BIO5192 hydrate  |  Natalizumab  |  Vedolizumab  |  α2β1 Integrin Ligand Peptide TFA  |  ICAM-1-IN-1  |  Zaurategrast ethyl ester  |  BIO5192

品牌介绍:
•   MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供*新*全的高品质小分子活性化合物；
•   10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；
•   设有专业的实验中心和严格的质控、验证体系；
•   提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；
•   产品的生物活性多经各国客户实验验证；
•   Nature, Cell, Science 等多种期刊及制药收录了MCE客户的科研成果；
•   专业团队跟踪*新的制药及生命科学研究进展，为您提供全球*新的活性化合物；
•   与世界各大制药公司及知名科研机构建立了长期的合作。