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Corylifol A

CAS No. : 775351-88-7

MCE 站：Corylifol A

产品活性：Corylifol A 能够抑制IL-6 诱导的 STAT3 的激活和磷酸化，其IC₅₀ 值为0.81 μM。

研究领域：JAK/STAT Signaling  |  Stem Cell/Wnt

作用靶点：STAT

In Vitro: Corylifol A shows an inhibitory effect on IL-6-induced STAT3 promoter activity in Hep3B cells with IC₅₀ value of 0.81±0.15 μM, also inhibits STAT3 phosphorylation induced by IL-6 in Hep3B cells. Corylifol A inhibits SARA PLpro in a dose-dependent manner with IC₅₀s ranging between 4.2 and 38.4 μM. Corylifol A is found to be a naturally occurring potent inhibitor of hCE2, with low K_i values ranging from 0.62 μM to 3.89 μM.

相关产品：Natural Product Library Plus  |  Bioactive Compound Library Plus  |  Immunology/Inflammation Compound Library  |  JAK/STAT Compound Library  |  Kinase Inhibitor Library  |  Stem Cell Signaling Compound Library  |  Natural Product Library  |  Small Molecule Immuno-Oncology Compound Library  |  Anti-Aging Compound Library  |  Differentiation Inducing Compound Library  |  Flavonoids Library  |  Anti-Breast Cancer Compound Library  |  Anti-Pancreatic Cancer Compound Library  |  Anti-Blood Cancer Compound Library  |  Stattic  |  AG490  |  Fludarabine  |  AS1517499  |  Niclosamide  |  Artesunate  |  Homoharringtonine  |  TPCA-1  |  Colivelin TFA  |  Cryptotanshinone  |  Napabucasin  |  Pimozide  |  STAT5-IN-1  |  C188-9  |  Scutellarin  |  BP-1-102  |  Cucurbitacin I  |  Saikosaponin D  |  Fraxinellone  |  Nifuroxazide  |  STAT3-IN-1  |  Alantolactone  |  Atractylenolide I  |  Dihydroisotanshinone I  |  FLLL32  |  HO-3867  |  Mogrol  |  Diosgenin  |  Garcinone D  |  HJC0152 hydrochloride

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