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Glucosamine hydrochloride

CAS No. : 66-84-2

MCE 站：Glucosamine hydrochloride

产品活性：Glucosamine hydrochloride (D-Glucosamine hydrochloride) 是一种氨基糖, 是糖基化蛋白和脂质生化合成的突出前体, 用作膳食补充剂。Glucosamine hydrochloride也是软骨基质和滑液中糖胺聚糖的天然成分，当外用时，对骨关节炎软骨和软骨细胞具有药理作用。

研究领域：Immunology/Inflammation  |  NF-κB  |  Metabolic Enzyme/Protease  |  Autophagy

作用靶点：Endogenous Metabolite  |  Reactive Oxygen Species  |  HIF/HIF Prolyl-Hydroxylase  |  Autophagy

In Vitro: Glucosamine hydrochloride (D-Glucosamine hydrochloride) exhibits dose-dependent DPPH antioxidant activity.
Glucosamine hydrochloride treatment of Short-term (4 h) inhibits HIF-1α at the protein level, decreases phosphorylation of p70S6K and S6, translation-related proteins.
Glucosamine hydrochloride significantly decreases renal expression of α-smooth muscle actin, collagen I, and fibronectin in the obstructed kidneys and TGF-β1-treated renal cells.

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