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Tedizolid phosphate

CAS No. : 856867-55-5

MCE 站：Tedizolid phosphate

产品活性：Tedizolid phosphate (TR-701FA) 是 MAO-A 和 MAO-B 抑制剂，具有抗革兰氏阳性菌的活性。

研究领域：Anti-infection

作用靶点：Bacterial  |  Antibiotic

In Vitro: Tedizolid phosphate (TR-701FA; 0.25 μg/mL) inhibits all 28 clinical isolates of PRSP, and is 4-fold more potent than linezolid against PRSP.

In Vivo: For mice infected with PSSP type III, the 100% survival rate is achieved with tedizolid phosphate (TR-701FA) at a minimum total daily dose of 10 mg/kg. Lungs of infected mice treated with tedizolid phosphate show less severe inflammation and edema, as indicated by the mean scores for inflammation and edema.

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