MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。

Palmatine chloride

CAS No. : 10605-02-4

MCE 站：Palmatine chloride

产品活性：Palmatine chloride 是一种口服活性的不可逆?IDO-1?抑制剂。 Palmatine chloride 可以减轻结肠损伤，预防肠道菌群失调和调节色氨酸分解代谢，从而改善 DSS 诱发的结肠炎。

研究领域：Metabolic Enzyme/Protease

作用靶点：Indoleamine 2,3-Dioxygenase (IDO)

In Vitro: Palmatine exhibits more potent IDO-1 inhibitory activity , which IC₅₀?on rhIDO-1 is 157 μM, and on HEK 293-hIDO-1 is 3 μM.

In Vivo: Palmatine (oral administration; 50 or 100 mg/kg, 7 days) has less distortion of epithelium, and fewer infiltrations of inflammatory cells, resulting in significantly lower histopathological scores, it also significantly suppresses the colonic MPO activity.

相关产品：Covalent Screening Library Plus  |  Natural Product Library Plus  |  Drug Repurposing Compound Library Plus  |  FDA-Approved Drug Library Plus  |  Bioactive Compound Library Plus  |  Immunology/Inflammation Compound Library  |  Metabolism/Protease Compound Library  |  Natural Product Library  |  FDA-Approved Drug Library  |  Anti-Cancer Compound Library  |  Small Molecule Immuno-Oncology Compound Library  |  Drug Repurposing Compound Library  |  Covalent Screening Library  |  NMPA-Approved Drug Library  |  Orally Active Compound Library  |  Traditional Chinese Medicine Monomer Library  |  FDA Approved & Pharmacopeial Drug Library  |  Alkaloids Library  |  Necrostatin-1  |  Indoximod  |  PF-06840003  |  Coptisine chloride  |  GNF-PF-3777  |  IDO-IN-3  |  IACS-8968 S-enantiomer  |  Coptisine Sulfate  |  Kushenol E  |  Palmatine  |  IDO-IN-11

品牌介绍:
•   MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供*新*全的高品质小分子活性化合物；
•   10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；
•   设有专业的实验中心和严格的质控、验证体系；
•   提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；
•   产品的生物活性多经各国客户实验验证；
•   Nature, Cell, Science 等多种期刊及制药收录了MCE客户的科研成果；
•   专业团队跟踪*新的制药及生命科学研究进展，为您提供全球*新的活性化合物；
•   与世界各大制药公司及知名科研机构建立了长期的合作。