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产品价格:电议      采购度:1601      原产地:美洲
发布时间:2021/7/21 17:14:05 所属地区:上海 上海市
简要描述:
D-glutamic acid是L-glutamic acid的对映异构体,广泛用于药物和食品中。
标签:(R)-Glutamic acid
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CAS No. : 6893-26-1
MCE 站:D-Glutamic acid
产品活性:D-glutamic acid是L-glutamic acid的对映异构体,广泛用于药物和食品中。
研究领域:Metabolic Enzyme/Protease
In Vitro: Various d-amino acids, such as D-serine, D-aspartic acid (D-Asp), and D-glutamic acid (D-Glu) are widely found in mammals including human beings and they are now thought to be the candidates of novel physiologically active substances and/or biomarkers. D-[Asp/Glu] (4 mg/mL) inhibits IgE binding (75%) to peanuts while D-Glu, D-Asp has no inhibitory effect. IgE is specific for D-[Asp/Glu] and may have the potential for removing IgE or reducing IgE binding to peanut allergens.
In Vivo: D-glutamic acid is currently paid attention as a modulator of neuronal transmission and hormonal secretion. It is metabolized only by D-aspartate oxidase in mammals. After intraperitoneal injection, L-glutamate is catabolized via a-ketoglutarate, whereas D-glutamate is converted to n-pyrrolidone carboxylic acid. Carbon 2 of both D- and L-glutamate is converted in the cecum to the methyl carbon of acetate. Both rat liver and kidney catalyze the conversion of D-glutamic acid to n-pyrrolidone carboxylic acid.
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更新时间:2024/1/2 10:14:03
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