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Tannic acid

CAS No. : 1401-55-4

MCE 站：Tannic acid

产品活性：Tannic acid 是一种新型的 hERG 通道阻塞剂，其IC₅₀ 值为 3.4 μM。

研究领域：Membrane Transporter/Ion Channel

作用靶点：Potassium Channel

In Vivo: During the course of treatment, tannic acid significantly ameliorates these phenotypes in AD skin lesions. Tannic acid treatment aslo reduces these dermal changes compare with AD mice. Treatment with tannic acid increases PPARγ expression in AD skin sections. The PPARγ protein expression is suppressed in vehicle-treated AD mice, but when treats with tannic acid, its expression is increased dramatically. The IL-1β, TNFα, TNFR1, and COX2 protein expressions are significantly up-regulated in vehicle-treated AD mice, but significantly suppressed by tannic acid treatment.

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