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Urotensin II, mouse

CAS No. :

MCE 站：Urotensin II, mouse

产品活性：Urotensin II, mouse 是孤儿 G 蛋白偶联受体 GPR14 或 SENR 的一种内源性配体。Urotensin II, mouse 是一种有效的血管收缩剂。在中枢神经系统中起着重要作用。

研究领域：GPCR/G Protein

作用靶点：Urotensin Receptor

In Vitro: This sequence of the C-terminus cyclic region of Urotensin II (U-II) is completely conserved in most species, including in the fish, frog, human, porcine, rat, and mouse, and it is thought to be essential for the agonistic activity of U-II. Urotensin II plays a physiological role in the central nervous system. Intracerebroventricular administration of Urotensin II induces anxiogenic-like behaviors in the elevated plus maze test and the hole-board test in mice in a dose-dependent manner, as do corticotropin releasing factor (CRF). The effective doses of Urotensin II are 10-100-fold higher than these of CRF in these tests.

In Vivo: Urotensin II is a somatostatin-like cyclic peptide which functions as an arterial vasocontrictor, vasodilator, and bronchoconstriction mediator.
Urotensin II (0.1 nmol, 0.3 nmol, and 3 nmol; intracerebroventricular administration) induces anxiogenic-like behaviors in the elevated plus maze test and the hole-board test in mice in a dose-dependent manner.

相关产品：Palosuran  |  Urotensin II, mouse TFA  |  SB-657510  |  Urotensin II (114-124), human TFA  |  UFP-803  |  [Orn5]-URP

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