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SLIGRL-NH2

CAS No. : 171436-38-7

MCE 站：SLIGRL-NH2

产品活性：SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) 是一种蛋白酶激活受体-2 (PAR-2) 激动剂。

研究领域：GPCR/G Protein

作用靶点：Protease-Activated Receptor (PAR)

In Vitro: SLIGRL-NH2 is an agonist of PAR-2 and MrgprC11. SLIGRL-NH2 causes an L-NAME-inhibited relaxation. Based on SLIGRL-NH₂ causing a concentration-dependent relaxation with an EC₅₀ of 10 ?M in endothelium-free preparations in the presence of perivascular adipose tissue (PVAT) , 20 ?M is used as a suitable ‘test’ concentration of peptide in subsequent experiments designed to evaluate the effects of potential inhibitors of ADRF release/action. In the endothelium-free aorta preparations, SLIGRL-NH2 causes a concentration-dependent relaxation in preparations only in the presence of PVAT [+PVAT, -ENDO (endothelium)].

相关产品：Bioactive Compound Library Plus  |  GPCR/G Protein Compound Library  |  Immunology/Inflammation Compound Library  |  TRAP-6  |  AZ3451  |  PAR-4 Agonist Peptide, amide TFA  |  SCH79797 dihydrochloride  |  Protease-Activated Receptor-2, amide  |  ENMD-1068 hydrochloride  |  TFLLR-NH2(TFA)  |  GB-110 hydrochloride  |  2-Furoyl-LIGRLO-amide  |  AC-55541  |  FSLLRY-NH2 TFA  |  Protease-Activated Receptor-4  |  Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA  |  tcY-NH2 TFA  |  AC-264613  |  Atopaxar  |  PAR 4 (1-6) (TFA)  |  Parstatin(human)  |  Parstatin(mouse)  |  Protease-Activated Receptor-1, PAR-1 Agonist  |  RWJ-56110 dihydrochloride  |  SLIGRL-NH2 TFA  |  tcY-NH2  |  TRAP-6 amide

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