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Ampicillin trihydrate

CAS No. : 7177-48-2

MCE 站：Ampicillin trihydrate

产品活性：Ampicillin trihydrate (D-(-)-α-Aminobenzylpenicillin trihydrate) 是一种广谱 β-内酰胺类抗生素，可对抗多种革兰氏阳性和革兰氏阴性细菌。

研究领域：Anti-infection

作用靶点：Bacterial  |  Antibiotic

In Vitro: Ampicillin trihydrate (D-(-)-α-Aminobenzylpenicillin trihydrate) inhibits the growth of E. coli of swine origin in a dose-dependent manner. The effective inhibitory concentration of Ampicillin trihydrate is 2.5 uG/mL.

In Vivo: Ampicillin trihydrate (D-(-)-α-Aminobenzylpenicillin trihydrate) is very effective in alleviating the symptoms of hemorrhagic enteritis in a 11-week old pig.
Ampicillin trihydrate produces maximum concentrations in bile twice as high as in serum. The peak concentration of ampicillin after an oral dose is as twice as high in portal blood as in peripheral blood.
Ampicillin trihydrate provides neuroprotection against ischemia-reperfusion brain injury. Ampicillin trihydrate reduces the activities of MMPs and increases the expression level of GLT-1. Pretreatment with Ampicillin trihydrate significantly reduces medial hippocampal cell death following global forebrain ischemia.

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