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Enocitabine

CAS No. : 55726-47-1

MCE 站：Enocitabine

产品活性：Enocitabine 是一种核苷类似物，是一种有效的 DNA 复制抑制剂和 DNA链终止剂。Enocitabine 抑制人巨细胞病毒的复制，具有抗白血病和抗病毒活性。

研究领域：Cell Cycle/DNA Damage  |  Anti-infection

作用靶点：Nucleoside Antimetabolite/Analog  |  DNA/RNA Synthesis  |  CMV

In Vitro: Enocitabine is resistant to deamination because Enocitabine bears a highly lipophilic group at the 4-amino position of the cytosine moiety of cytarabine.
The combined effects of Pirarubicin and Enocitabine on HeLa S3 human uterine cervix carcinoma and K562 human myelocytic leukemia cells are determined by enhancement of their cytotoxic activities. Enocitabine or etoposide shows synergistic effects on HeLa S3 and K562 cells.
In the presence of Enocitabine, triphosphate forms of the nucleoside analogs are detected in the human cytomegalovirus (HCMV)-infected cells, and synthesis of HCMV DNA is strongly suppressed.

相关产品：Natural Product Like Compound Library  |  Bioactive Compound Library Plus  |  Anti-Infection Compound Library  |  Cell Cycle/DNA Damage Compound Library  |  Anti-Cancer Compound Library  |  Antiviral Compound Library  |  Anti-Aging Compound Library  |  Reprogramming Compound Library  |  Glycoside Compound Library  |  Nucleotide Compound Library  |  Anti-Blood Cancer Compound Library  |  Cycloheximide  |  5-Fluorouracil  |  Oxaliplatin  |  Gemcitabine  |  Decitabine  |  Actinomycin D  |  5-Azacytidine  |  Mitomycin C  |  Bleomycin sulfate  |  Carboplatin  |  Cytarabine  |  5-BrdU  |  Favipiravir  |  Methotrexate  |  Streptozocin  |  Anisomycin  |  Fludarabine  |  Thymidine  |  Epirubicin hydrochloride  |  Daunorubicin hydrochloride  |  Capecitabine  |  Hydroxyurea  |  Plicamycin  |  Ganciclovir  |  Adenosine  |  Urolithin A  |  Brequinar  |  Folic acid

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