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Fenoterol hydrobromide

CAS No. : 1944-12-3

MCE 站：Fenoterol hydrobromide

产品活性：Fenoterol hydrobromide (Th-1165a) 是拟交感神经剂，是一种选择性的，具有口服活性 β2-肾上腺素受体 (β2-adrenoceptor) 激动剂。Fenoterol hydrobromide 是一种有效的支气管扩张剂，可用于与哮喘，支气管炎和其他阻塞性气道疾病相关的支气管痉挛的研究。

研究领域：GPCR/G Protein  |  Neuronal Signaling

作用靶点：Adrenergic Receptor

In Vitro: Fenoterol (1 μM; pre-incubated 30 minutes) treatment reduces AICAR-induced AMPK activation, NF-κB activation and TNF-α release, and also significantly downregulates the elevated phosphorylation levels of AMPK.
Fenoterol inhibits lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells.
Fenoterol is also a potent exosome biogenesis and/or secretion activator in PC cells.

In Vivo: Fenoterol (0.7 mg/kg; intraperitoneal injection; twice a day; for 3 weeks) treatment suppresses mechanical allodynia during chronic treatment.

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