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Imidapril hydrochloride

CAS No. : 89396-94-1

MCE 站：Imidapril hydrochloride

产品活性：Imidapril hydrochloride (TA-6366) 是血管紧张素转换酶 (ACE) 抑制剂，具有抗高血压活性。

研究领域：Metabolic Enzyme/Protease

作用靶点：Angiotensin-converting Enzyme (ACE)

In Vitro: As a prodrug, Imidapril is converted by hydrolysis in the liver into its active form imidaprilat. Imidaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Imidaprilat also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.

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