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Fosmidomycin sodium salt

CAS No. : 66508-37-0

MCE 站：Fosmidomycin sodium salt

产品活性：Fosmidomycin sodium salt 是一种磷酸抗生素和抗疟疾药，对革兰氏阴性菌和革兰氏阳性菌均有活性。

研究领域：Anti-infection

作用靶点：Bacterial  |  Antibiotic

In Vitro: Fosmidomycin sodium salt is a phosphonic acid antibiotic, which is active against both Gram-negative and Gram-positive bacteria.

In Vivo: Animals treated intraperitoneally with dosages of >10 mg/kg of fosmidomycin are apparently free of parasites. After treatment with 5 mg/kg of fosmidomycin, parasitemias are <1%. Animals treated orally with 50 or 100 mg/kg of fosmidomycin are apparently free of parasites, and parasitemias are <1% after treatment with 20 mg/kg of drug. Recrudescence is observed when the treatment is terminated after 4 days. Mice treated with 30 mg/kg of fosmidomycin over a period of 8 days are totally cured.

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