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Protease-Activated Receptor-1, PAR-1 Agonist TFA

CAS No. :

MCE 站：Protease-Activated Receptor-1, PAR-1 Agonist TFA

产品活性：Protease-Activated Receptor-1, PAR-1 Agonist TFA 是一种选择性蛋白酶激活受体1 (PAR-1) 激动肽。Protease-Activated Receptor-1, PAR-1 Agonist TFA 对应于 PAR1 配体，可通过该受体选择性地模拟凝血酶的作用。

研究领域：GPCR/G Protein

作用靶点：Protease-Activated Receptor (PAR)

In Vitro: Protease-Activated Receptor-1, PAR-1 Agonist induces activation of protein kinase C isoenzymes alpha ａnd epsilon in human HT-29 colon carcinoma cells expressing PAR1 endogeneously. On the cellular level, Protease-Activated Receptor-1, PAR-1 Agonist ａnd thrombin prompted HT-29 cell migration ａnd matrix adhesion by a PKCepsilon-dependent mechanism as concluded because of the inhibition of PAR1-mediated effects by the PKC inhibitor bisindolylmaleimide I ａnd the PKCepsilon translocation inhibitory peptide EAVSLKPT but not by the PKC inhibitor Gö 6976.

相关产品：Bioactive Compound Library Plus  |  GPCR/G Protein Compound Library  |  Immunology/Inflammation Compound Library  |  Anti-Cancer Compound Library  |  Vorapaxar  |  TRAP-6  |  AZ3451  |  PAR-4 Agonist Peptide, amide TFA  |  I-191  |  SCH79797 dihydrochloride  |  ENMD-1068 hydrochloride  |  GB-88  |  SLIGRL-NH2  |  Protease-Activated Receptor-2, amide  |  GB-110 hydrochloride  |  TFLLR-NH2(TFA)  |  2-Furoyl-LIGRLO-amide  |  FSLLRY-NH2 TFA  |  Parmodulin 2  |  AC-55541  |  PZ-128  |  PAR-2-IN-1  |  Protease-Activated Receptor-4  |  tcY-NH2 TFA  |  Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA  |  AC-264613  |  Atopaxar  |  CBK289001  |  PAR 4 (1-6) (TFA)  |  Parstatin(human)

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