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Antiviral Compound Library

MCE 站：Antiviral Compound Library

Viruses are much simpler organisms than bacteria, ａnd they are made from protein substances ａnd nucleic acid. Despite the fact that the exact mechanism of infection is extremely specific to each type of virus, the general scheme of infection can be represented in the following manner: A virus is absorbed at the surface of a host cell ａnd then permeates through the membrane, where it releases nucleic acid from its protein protection. Then the viral nucleic acid begins to replicate, ａnd transcription of the viral genome takes place either in the cytoplasm, or in the nucleus of the host cell. As a result of these events, a large amount of viral nucleic acid ａnd protein are made to make new generations of virions. Therefore, one mechanism of action of antiviral drugs is to interfere with the ability of a virus to get into a target cell. A second mechanism of action is to target the processes that synthesize virus components after a virus invades a cell, such as nucleotide or nucleoside analogs. MCE designs a unique collection of 596 anti-virus compounds that target several viruses, including SARS-CoV, HBV, HCV, HIV, HSV ａnd Influenza Virus. It’s an effective tool for anti-virus drug discovery.

Description & Advantages:

•   A unique collection of 596 bioactive anti-virus compounds for high throughput screening (HTS) ａnd high content screening (HCS).

•   Targets include HBV, HCV, HIV, HSV, Influenza Virus, Reverse Transcriptase, etc.

•   A useful tool for the discovery of anti-virus drugs.

•   Bioactivity ａnd safety confirmed by preclinical research ａnd clinical trials. Some have been approved by FDA.

•   Structurally diverse, medicinally active, ａnd cell permeable.

•   Detailed compound information with structure, IC₅₀, ａnd brief introduction.

•   Validated NMR ａnd HPLC to ensure high purity ａnd quality.

•   All compounds are in stock ａnd continuously updated.

品牌介绍:
•   MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供*新*全的高品质小分子活性化合物；
•   10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；
•   设有专业的实验中心和严格的质控、验证体系；
•   提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；
•   产品的生物活性多经各国客户实验验证；
•   Nature, Cell, Science 等多种期刊及制药收录了MCE客户的科研成果；
•   专业团队跟踪*新的制药及生命科学研究进展，为您提供全球*新的活性化合物；
•   与世界各大制药公司及知名科研机构建立了长期的合作。