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FM4-64

CAS No. : 162112-35-8

MCE 站：FM4-64

产品活性：FM4-64 是一种膜选择性红色荧光染料，属于苯乙烯基吡啶染料FM家族。FM4-64 被广泛用于研究活体动物的内吞和外吞、囊泡运输和细胞器组织。

研究领域：Others

作用靶点：Others

In Vitro: FM4-64 readily translocates to the nuclear envelope (NE) at physiological temperature where it exhibits enhanced fluorescence when excited at 620-650 nm in contrast to 480-520 nm excitation in the endocytic pathway ａnd in the endoplasmic reticulum (ER). In vitro data indicated that the dye reveals an enrichment of negatively charged lipids, presumably due to local phospholipid synthesis. Dual-excitation imaging of FM4-64 in relation to lamina-associated polypeptide-1-green fluorescent protein during mitosis suggested that the disassembly of NE preserves microscale lipid complexes in the ER.
For studies onplant ａnd fungal cells, FM4-64 is usually preferred to FM1-43 due to its superior brightness, greater contrast, higher photostability, ａnd its red-shifted emission facilitating concomitantuse with the green fluorescent protein (GFP).

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