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产品价格:电议      采购度:1620      原产地:美洲
发布时间:2021/11/4 18:32:34 所属地区:国外 国外
简要描述:
"Erythromycin Mupirocin (BRL-4910A) 是从 Pseudomonas fluorescens 中分离得到的一种有口服活性的抗生素。Mupirocin (BRL-4910A) 通过可逆地抑制异亮氨酸转移RNA,从而抑制细菌蛋白和R
标签:E-Bactroban
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CAS No. : 12650-69-0
MCE 站:Mupirocin
产品活性:Mupirocin (BRL-4910A) 是从 Pseudomonas fluorescens 中分离得到的一种有口服活性的抗生素。Mupirocin (BRL-4910A) 通过可逆地抑制异亮氨酸转移RNA,从而抑制细菌蛋白和RNA的合成而发挥抗菌作用。
研究领域:Anti-infection
作用靶点:Bacterial | Antibiotic
In Vitro: Mupirocin (BRL-4910A) shows a high level of activity against staphylococci and streptococci and against certain gram-negative bacteria. Mupirocin (BRL-4910A) is highly bound (95% bound) to the protein of human serum, and activity was reduced 10- to 20-fold in the presence of human serum.
In Vivo: Mupirocin is well absorbed after oral and parenteral administration but serum antibiotic concentrations were short-lived as a result of extensive degradation to the antibacterially inactive metabolite, monic acid A.
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更新时间:2024/1/2 10:18:59
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