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Neurodegenerative Disease-related Compound Library

MCE 站：Neurodegenerative Disease-related Compound Library

Neurodegenerative diseases are incurable ａnd life-threatening conditions that result in progressive degeneration and/or death of nerve cells. Some common neurodegenerative diseases include Alzheimer’s Disease (AD), Parkinson’s Disease (PD), Motor Neuron Disease (MND), Huntington’s Disease (HD), Spino-Cerebellar Ataxia (SCA), Spinal Muscular Atrophy (SMA), ａnd Amyotrophic Lateral Sclerosis (ALS). Because the pathophysiology of neurodegenerative disorders is generally poorly understood, it is difficult to identify promising molecular targets ａnd validate them. At the same time, about 85% of the drugs fail in clinical trials. Therefore, validating new targets ａnd discovering new drugs to mitigate neurodegenerative disorders is need of the hour. MCE offers a unique collection of 1368 compounds with anti-Neurodegenerative Diseases activities or targeting the unique targets of neurodegenerative diseases. MCE Neurodegenerative Disease-related Compound Library is a useful tool for exploring the mechanism of neurodegenerative diseases ａnd discovering new drugs for neurodegenerative diseases.

Description & Advantages:

•   A unique collection of 1368 compounds for high throughput screening (HTS) ａnd high content screening (HCS).

•   Targets include Amyloid-β, Dopamine Receptor, COMT, LRRK2, 5-HT Receptor, Monoamine Oxidase, nAChR, Histamine Receptor, etc.

•   A useful tool for exploring the mechanism of neurodegenerative diseases ａnd looking for new treatments.

•   Bioactivity ａnd safety confirmed by clinical trials or preclinical research. Some have been approved by FDA.

•   Structurally diverse, medicinally active, ａnd cell permeable.

•   Detailed compound information with structure, IC₅₀, ａnd brief introduction.

•   High purity ａnd quality validated by NMR ａnd LC/MS.

•   All compounds are in stock ａnd continuously updated.

品牌介绍:
•   MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供*新*全的高品质小分子活性化合物；
•   10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；
•   设有专业的实验中心和严格的质控、验证体系；
•   提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；
•   产品的生物活性多经各国客户实验验证；
•   Nature, Cell, Science 等多种期刊及制药收录了MCE客户的科研成果；
•   专业团队跟踪*新的制药及生命科学研究进展，为您提供全球*新的活性化合物；
•   与世界各大制药公司及知名科研机构建立了长期的合作。