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Calcium Channel Blocker Library

MCE 站：Calcium Channel Blocker Library

Calcium channel blockers (CCBs), also called calcium antagonists are compounds that slow the movement of calcium (Ca2+) through calcium channels into the cells of the heart ａnd blood vessel walls. Calcium causes the heart ａnd arteries to squeeze more strongly. By blocking calcium, calcium channel blockers allow blood vessels to relax ａnd open. So calcium channel blockers are usually used to lower blood pressure, relieve chest pain (angina) ａnd control an irregular heartbeat.MCE supplies a unique collection of 123 calcium channel blockers ａnd antagonists, all of which have the identified inhibitory effect on calcium channel. MCE Calcium Channel Blocker Library is a useful tool for discovery of antihypertensive drugs ａnd cardiovascular disease research.

Description & Advantages:

   A unique collection of 123 calcium channel blockers ａnd antagonists for high throughput screening (HTS) ａnd high content screening (HCS).

    A useful tool for the discovery of antihypertensive drugs ａnd anti-cardiovascular drugs.

   Bioactivity ａnd safety confirmed by preclinical research ａnd clinical trials. Some have been approved by FDA.

   Structurally diverse, medicinally active, ａnd cell permeable.

   Detailed compound information with structure, IC50, ａnd brief introduction.

   High purity ａnd quality validated by NMR ａnd LC/MS.

   All compounds are in stock ａnd continuously updated.

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