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Non-steroidal Anti-Inflammatory Compound Library

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产品价格:电议      采购度:1191      原产地:美洲

发布时间:2022/9/28 22:03:16      所属地区:国外 国外

简要描述:

Non-steroidal anti-inflammatory drugs (NSAIDs) are members of a therapeutic drug class with potent anti-inflammatory, analgesic an

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Non-steroidal Anti-Inflammatory Compound Library

MCE 站:Non-steroidal Anti-Inflammatory Compound Library

Non-steroidal anti-inflammatory drugs (NSAIDs) are members of a therapeutic drug class with potent anti-inflammatory, analgesic and antipyretic activity, and are among the most widely used drugs worldwide. The most prominent NSAIDs are aspirin, ibuprofen, and naproxen. The main mechanism of action of NSAIDs is the inhibition of the enzyme cyclooxygenase (COX), based on which NSAIDs can be classified into two types: non-selective and COX-2 selective. Most NSAIDs are non-selective and inhibit both COX-1 and COX-2 activity. MCE offers a unique collection of 538 non-steroidal compounds with identified anti-inflammatory activity. MCE non-steroidal anti-inflammatory library is a useful tool for the study of anti-inflammatory drugs and pharmacology.

Description & Advantages:

    A unique collection of 538 bioactive non-steroidal anti-Inflammatory compounds for high throughput screening (HTS) and high content screening (HCS).

    A useful tool for the study of anti-inflammatory drugs and pharmacology.

    Target diverse, medicinally active and cell permeable.

    Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

    More detailed compound information with structure, IC50, and other chemical & biological data.

    High purity and quality validated by NMR and LC/MS.

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更新时间:2024/1/2 10:26:55

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