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Marine-Sourced Natural Product Library

MCE 站：Marine-Sourced Natural Product Library

Oceans cover more than 70% of the Earth’s surface ａnd host a huge species diversity. Marine organisms are considered the most recent source of bioactive natural products after terrestrial plants ａnd nonmarine microorganisms. Marine biological sources are taxonomically diverse ａnd include sponges, tunicates, corals, mollusks, fungi, ａnd sediment-derived bacteria. Marine organisms can produce a plethora of small molecules with novel chemical structures ａnd potent biological properties, being a rich source for the discovery of pharmacologically active compounds, already with several marine-derived agents approved as drugs. Ziconotide, a peptide originally discovered in a tropical cone snail, was the first marine-derived compound to be approved in the United States in December 2004 for the treatment of pain. Then, in October 2007, Trabectedin became the first marine anticancer drug to be approved in the European Union. MCE offers a unique collection of 36 marine-sourced natural products which can be used for drug discovery for high throughput screening (HTS) ａnd high content screening (HCS). MCE marine-sourced natural product library is an important source for drug discovery ａnd development.

Description & Advantages:

    A unique collection of 36 marine-sourced natural products for high throughput screening (HTS) ａnd high content screening (HCS).

    A useful tool for the study of critical for drug discovery ａnd development.

    Target diverse, medicinally active ａnd cell permeable.

    Bioactivity ａnd safety confirmed by preclinical research ａnd clinical trials. Some have been approved by FDA.

    More detailed compound information with structure, IC₅₀, ａnd other chemical & biological data.

    High purity ａnd quality validated by NMR ａnd LC/MS.

品牌介绍:
•   MCE (MedChemExpress) 拥有200 多种全球独家化合物库，我们致力于为全球科研客户提供前沿*全的高品质小分子活性化合物；
•   50,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领；
•   产品种类涵盖各种重组蛋白，多肽，常用试剂盒 ，更有 PROTAC、ADC 等特色产品，广泛应用于新药研发、生命科学等科研项目；
•   提供虚拟筛选，离子通道筛选，代谢组学分析检测分析，药物筛选等专业技术服务；
•   设有专业的实验中心和严格的质控、验证体系；
•   提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；
•   产品的生物活性多经各国客户实验验证；
•   Nature, Cell, Science 等多种期刊及制药收录了MCE客户的科研成果；
•   专业团队跟踪*新的制药及生命科学研究进展，为您提供全球*新的活性化合物；
•   与世界各大制药公司及知名科研机构建立了长期的合作。