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MCP-1/CCL2 Protein, Rat (HEK293, C-His)

MCE 站：MCP-1/CCL2 Protein, Rat (HEK293, C-His)

MCP-1/CCL2 Protein, Rat (HEK293, His) 是属于CC趋化因子家族的细胞因子。

Synonyms: rRtMCP-1/CCL2; C-C motif chemokine 2; MCAF; MCP-1; SCYA2

Species: Rat

Source: HEK293

Biological Activity: The ED₅₀ is <0.3 μg/mL as measured by CHO-K1/Gα15/rCCR2 cells (human Gα15 ａnd rat CCR2 stably expressed in CHO-K1 cells).

研究背景：CCL2 is produced by a variety of cell types, either constitutively or after induction by oxidative stress, cytokines, or growth factors. CCL2 is produced by many cell types, including endothelial, fibroblasts, epithelial, smooth muscle, mesangial, astrocytic, monocytic, ａnd microglial cells. CCL2 regulates the migration ａnd infiltration of monocytes, memory T lymphocytes, ａnd natural killer (NK) cells. The chemokine CCL2 ａnd its main chemokine receptor CCR2 have been implicated in the pathogenesis of several different disease processes, including vascular permeability ａnd attraction of immune cells during metastasis, a number of different neurological disorders, autoimmune disease, obesity, ａnd atherosclerosis.

蛋白编号：P14844 (Q24-N148)

基因 ID：24770

产品分类：细胞因子和生长因子  |  趋化因子  |  CC 趋化因子  |  趋化因子 CCL2

Categories：Cytokines ａnd Growth Factors  |  Chemokine & Receptors  |  CC Chemokines  |  MCP-1/CCL2

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