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CD20/MS4A1 Protein, Human (Trx-His, Solution)

MCE 站：CD20/MS4A1 Protein, Human (Trx-His, Solution)

CD20/MS4A-1 Protein,Human (Trx-His) 是 B 淋巴细胞发育过程中表达的一种完整的膜蛋白。

Synonyms: rHuB-lymphocyte antigen CD20/CD20, Trx-His; MS4A1; CD20; MS4A-1; B1; Bp35; CVID5; LEU-16; MS4A2; S7

Species: Human

Source: E. coli

Biological Activity: Data is not available.

研究背景：CD20 is an non-glycosylated protein expressed on the surface of normal ａnd malignant B lymphocytes, ａnd belongs to the MS4A (membrane-spanning 4-domain family A) protein family. Human cluster of differentiation 20 (CD20) is an integral membrane protein expressed during B lymphocyte development. CD20 it is involved in intracellular calcium signaling associated with the B cell receptor. CD20 is also expressed in malignant B cells ａnd is the target of approved therapeutic monoclonal antibodies (mAbs), which are divided into two groups, type I ａnd type II, on the basis of two signature differences: Type I mAbs recruit complement more potently than type II mAbs ａnd therefore induce robust complement-dependent cytotoxicity (CDC); type I mAbs bind twice as many type II mAbs to a given B cell type.

蛋白编号：P11836 (I141-S188)

基因 ID：931

产品分类：CD 抗原  |  B 细胞 CD 蛋白  |  CD20  |  CD 抗原  |  巨噬细胞 CD 蛋白  |  CD20  |  CD 抗原  |  干细胞 CD 蛋白  |  CD20  |  CD 抗原  |  树突细胞 CD 蛋白  |  CD20  |  CAR-T 相关蛋白  |  CD20

Categories：CD Antigens  |  B Cell CD Proteins  |  CD20  |  CD Antigens  |  Macrophage CD Proteins  |  CD20  |  CD Antigens  |  Stem Cell CD Proteins  |  CD20  |  CD Antigens  |  Dendritic Cell CD Proteins  |  CD20  |  CAR-T related Proteins  |  CD20

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