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Quinidine (15% dihydroquinidine)

CAS No. : 56-54-2

MCE 站：Quinidine (15% dihydroquinidine)

产品活性：Quinidine (15% dihydroquinidine) 是一种抗心律失常剂。Quinidine 是一种有效的、具有口服活性的、选择性的细胞色素 P450db (cytochrome P450db) 抑制剂，也是 K⁺ 通道 (K⁺ channel) 的有效阻断剂，其 IC₅₀ 值为 19.9 μM，也可诱导凋亡。Quinidine 也可用作疟疾的研究。

研究领域：Membrane Transporter/Ion Channel  |  Metabolic Enzyme/Protease  |  Apoptosis  |  Anti-infection

作用靶点：Potassium Channel  |  Cytochrome P450  |  Apoptosis  |  Parasite

结构分类：生物碱  |  喹啉类生物碱  |  结构分类

来源：植物  |  其他科

In Vitro: Quinidine shows cytotoxicity against MES-SA cells, ａnd induces apoptosis.

In Vivo: Quinidine shows effects on the PTZ-induced seizure threshold.

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