MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。

7-Methoxy-1-tetralone

CAS No. : 6836-19-7

MCE 站：7-Methoxy-1-tetralone

产品活性：7-Methoxy-1-tetralone 是一种强效的抗肿瘤试剂。7-Methoxy-1-tetralone 抑制癌细胞增殖和迁徙，并诱导肝细胞癌细胞 (HCC) 凋亡 (apoptosis)。7-Methoxy-1-tetralone 能够降低 NF-κB、基质金属肽酶 2 (MMP2)/MMP9 和 p-AKT 的蛋白水平。7-Methoxy-1-tetralone 在裸鼠体内具有抗肿瘤活性，对体重和肝脾脏器指数没有影响。

研究领域：Apoptosis  |  NF-κB  |  Protein Tyrosine Kinase/RTK  |  PI3K/Akt/mTOR  |  Metabolic Enzyme/Protease

作用靶点：Apoptosis  |  NF-κB  |  c-Met/HGFR  |  Akt  |  MMP

In Vitro: 7-Methoxy-1-tetralone (31.25-1000 μM; 48 h) inhibits proliferative activity of LO2 ａnd HepG2 cells.
7-Methoxy-1-tetralone (40 μM, 100 μM, ａnd 250 μM; 48 h) induces HepG2 cell apoptosis, ａnd decreases the protein expression levels of c-Met, p-AKT, AKT, NF-κB, MMP2, ａnd MMP9 in cells.

In Vivo: 7-Methoxy-1-tetralone (80, 120, or 160 mg/kg/d; ip; 19 doses in total) inhibits tumor growth in subcutaneously implanted tumor model with HepG2 cells.

相关产品：Bioactive Compound Library Plus  |  Apoptosis Compound Library  |  Immunology/Inflammation Compound Library  |  Kinase Inhibitor Library  |  Metabolism/Protease Compound Library  |  NF-κB Signaling Compound Library  |  PI3K/Akt/mTOR Compound Library  |  Protein Tyrosine Kinase Compound Library  |  Stem Cell Signaling Compound Library  |  Anti-Cancer Compound Library  |  Autophagy Compound Library  |  Fragment Library  |  Anti-Aging Compound Library  |  Antioxidant Compound Library  |  Differentiation Inducing Compound Library  |  Oxygen Sensing Compound Library  |  Glycolysis Compound Library  |  Pyroptosis Compound Library  |  Cytoskeleton Compound Library  |  Glutamine Metabolism Compound Library  |  Anti-Breast Cancer Compound Library  |  Anti-Lung Cancer Compound Library  |  Anti-Pancreatic Cancer Compound Library  |  Anti-Blood Cancer Compound Library  |  Anti-Cancer Metabolism Compound Library  |  Anti-Obesity Compound Library  |  Angiogenesis-Related Compound Library  |  Transcription Factor-Targeted Library  |  Glucose Metabolism Compound Library  |  Anti-Liver Cancer Compound Library   |  Anti-Colorectal Cancer Compound Library   |  Antidepressant Compound Library  |  Anti-Prostate Cancer Compound Library  |  Anti-Pulmonary Fibrosis Compound Library  |  Cancer Stem Cells Compound Library  |  Pain-Related Compound Library  |  Membrane Protein-targeted Compound Library  |  Membrane Receptor-targeted Compound Library  |  Cytokine Inhibitors Library  |  Cell Death Library  |  Serine/Threonine Kinase Inhibitor Library  |  SY-5609  |  BRD4 Inhibitor-18  |  8α-Tigloyloxyhirsutinolide 13-O-acetate  |  AAPK-25  |  Dutasteride-¹³C₆  |  Oleic acid-¹³C  |  Anticancer agent 120  |  Abacavir sulfate  |  Meloxicam-d₃-1  |  AMG-208  |  Thailanstatin D  |  SB-218078  |  Toyocamycin  |  Sorafenib-d₄  |  IMD-ferulic  |  DS-1205b free base  |  Busulfan  |  Karacoline  |  PTC-028  |  5-Hydroxy tryptophol β-D-glucuronide-d₄  |  Dinaciclib  |  CR-1-31-B  |  142I5  |  Doxycycline calcium  |  Farudodstat  |  Ecteinascidin 770  |  AT9283  |  Staurosporine  |  SNS-032  |  LM22B-10

热门产品线：重组蛋白  |  化合物库  |  天然产物  |  荧光染料  |  PROTAC  |  同位素标记物  |  寡核苷酸  |  抗体  |  点击化学

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent Dye  |  PROTAC  |  Isotope-Labeled Compounds  |  Oligonucleotides  |  Antibodies  |  Click Chemistry

品牌介绍:
•   MCE (MedChemExpress) 拥有200 多种全球独家化合物库，我们致力于为全球科研客户提供前沿*全的高品质小分子活性化合物；
•   50,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领；
•   产品种类涵盖各种重组蛋白，多肽，常用试剂盒 ，更有 PROTAC、ADC 等特色产品，广泛应用于新药研发、生命科学等科研项目；
•   提供虚拟筛选，离子通道筛选，代谢组学分析检测分析，药物筛选等专业技术服务；
•   设有专业的实验中心和严格的质控、验证体系；
•   提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；
•   产品的生物活性多经各国客户实验验证；
•   Nature, Cell, Science 等多种期刊及制药收录了MCE客户的科研成果；
•   专业团队跟踪*新的制药及生命科学研究进展，为您提供全球*新的活性化合物；
•   与世界各大制药公司及知名科研机构建立了长期的合作。