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Cytokine Inhibitors Library

MCE 站：Cytokine Inhibitors Library

Cytokines are a kind of low molecular soluble proteins synthesized ａnd secreted by immunogen, mitogen or other factors. They have functions of regulating innate ａnd adaptive immune responses, promoting hematopoiesis, stimulating cell activation, proliferation ａnd differentiation. The process of releasing a large number of cytokines is also called “Cytokine storm”, which can cause damage to many tissues ａnd organs in the body. Cytokine is involved in the pathogenesis of many human diseases, including cancer, diabetes, chronic inflammatory diseases ａnd so on. Cytokine inhibitors are a class of essential compounds that act by directly inhibiting the synthesis ａnd release of cytokine or blocking the binding of cytokine to their receptors. Cytokine inhibitors are important compounds for the study of tumor ａnd autoimmune diseases. MCE designs a unique collection of 964 cytokine inhibitors, mainly targeting the receptor interleukin (IL), colony-stimulating factor (CSF), interferon (IFN), tumor necrosis factor (TNF), growth factor (GF) ａnd chemokine, which is an effective tool for development ａnd research of anti-cancer, anti-chronic inflammatory diseases ａnd anti-autoimmune diseases compounds.

Description & Advantages:

    A unique collection of 964 cytokine inhibitors for high throughput screening (HTS) ａnd high content screening (HCS).

   The library contains compounds targeting the receptor interleukin (IL), colony-stimulating factor (CSF), interferon (IFN), tumor necrosis factor (TNF), growth factor (GF) ａnd chemokine.

   A useful tool for the discovery of anti-cancer, anti-chronic inflammatory diseases ａnd anti-autoimmune diseases compounds

   Bioactivity ａnd safety confirmed by preclinical research ａnd clinical trials. Some have been approved by FDA.

   Structurally diverse, bioactive, ａnd cell permeable.

   More detailed compound information with structure, IC50, ａnd other chemical & biological data.

   High purity ａnd quality validated by NMR ａnd LC/MS.

   All compounds are in stock ａnd continuously updated.

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