MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。

1-Benzylimidazole

CAS No. : 4238-71-5

MCE 站：1-Benzylimidazole

产品活性：1-Benzyl-1H-imidazole 是一种生化试剂，可作为生物材料或有机化合物，用于生命科学相关研究。

研究领域：Others

作用靶点：Biochemical Assay Reagents

In Vitro: Benzylimidazole is a selective inhibitor of thromboxane synthase ａnd a stimulator of UDP-glucuronosyltransferase. Thromboxane synthase is a cytochrome P450 enzyme. The cytochrome P450 proteins have been involved in catalyzing many reactions invol ved in drug metabolism ａnd synthesis of cholesterol, steroids , ａnd other lipids. The enzyme plays an important role in several pathophysiological processes including hemostasis, cardiovascular disease, ａnd stroke. The gene expresses two transcript variants. 1-Benzylimidazole selectively inhibited the activity of thrombus Boxane synthase. 1-Benzylimidazole reduced TXB2 levels ａnd increased blood flow in ischemia-reperfusion injury of rat brain. In male Wistar rats, gastrically administration of 1-benzylimidazole (25, 75 ａnd 100 mg/kg/day) caused a dose-dependent hepatitis. 1-Benzylimidazole decreased the plasma level in triglycerides by 6070%. 1-benzylimidazole stimulated three distinct forms of UDP-glucuronosyltransferase. 1-benzylimidazole significantly increased the activities towards 4-methylumbelliierone, 1-naphthol, morphine or a monoterpenoid alcohol, nopol. Benzylimidazole increased hepatocellular CYP1A catalytic activity ａnd CYP1A mRNA in a concentration-dependent way.

相关产品：Levoglucose  |  2,6-Difluoropyridine  |  HPMC (Type I,Viscosity:400mPa.s)  |  (R)-3-(Boc-amino)pyrrolidine  |  Maltotriose hydrate  |  Methyl β-D-arabinopyranoside  |  Methyl 12-aminododecanoate hydrochloride  |  Methyl undec-10-enoate  |  EDTA-AM  |  DDMAB  |  4,4＇-Bibenzoic acid  |  Antitumor agent-106  |  Allyl heptanoate  |  Octyl α-D-glucopyranoside  |  Nonyl-β-D-1-thiomaltoside  |  trans-2-Undecenal  |  4-Nitrophthalonitrile  |  Homobrassinolide  |  2-Chloronicotinaldehyde  |  3-Methoxypyridine  |  Orange G  |  2,5-Dibromothiazole  |  (Boc-aminooxy)acetic acid  |  Tetrahexylammonium bromide  |  4-(Diphenylamino)benzeneboronic acid  |  3-Chloro-2,4-difluorobenzoic acid  |  Dibenzo[b,d]furan  |  FITC-Dextran (MW 110000)  |  5-Bromopyridin-2-ol  |  Anti-inflammatory agent 43

热门产品线：重组蛋白  |  化合物库  |  天然产物  |  荧光染料  |  PROTAC  |  同位素标记物  |  寡核苷酸  |  抗体  |  点击化学

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent Dye  |  PROTAC  |  Isotope-Labeled Compounds  |  Oligonucleotides  |  Antibodies  |  Click Chemistry

品牌介绍:
•   MCE (MedChemExpress) 拥有200 多种全球独家化合物库，我们致力于为全球科研客户提供前沿*全的高品质小分子活性化合物；
•   50,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领；
•   产品种类涵盖各种重组蛋白，多肽，常用试剂盒 ，更有 PROTAC、ADC 等特色产品，广泛应用于新药研发、生命科学等科研项目；
•   提供虚拟筛选，离子通道筛选，代谢组学分析检测分析，药物筛选等专业技术服务；
•   设有专业的实验中心和严格的质控、验证体系；
•   提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；
•   产品的生物活性多经各国客户实验验证；
•   Nature, Cell, Science 等多种期刊及制药收录了MCE客户的科研成果；
•   专业团队跟踪*新的制药及生命科学研究进展，为您提供全球*新的活性化合物；
•   与世界各大制药公司及知名科研机构建立了长期的合作。